Research

Mission

The LIMES Institute hosts groups with major research expertise in

Chemical Biology & Medicinal Chemistry,
Development, Molecular Physiology & Genetics,
Molecular Cell & Immune Biology and
Membrane Biology & Biochemistry.

Using genetic model organisms (Drosophila, mouse), murine and human tissue culture cells and lipid and membrane biochemistry approaches, we aim at identifying and functionally characterizing novel key regulators controlling metabolism, cellular growth and local immunity. Chemical Biology approaches such as small molecule screening, combined with chemo- and bioinformatics, are used to identify novel chemical inhibitors which we use to modulate the function of these regulatory proteins in cells and model organisms. We are also interested in the identification of human patients with mutations in the novel genes that we have identified and characterized.

The LIMES Institute has been tailored to facilitate and accelerate progress in Life Sciences and Biomedicine using highly interdisciplinary approaches in the postgenomic era. In addition, the LIMES institute harbours core facilities essential for cutting-edge research in the life sciences, for the coordination of the LIMES teaching programs, for the IT administration and the public relations of the institute.

Faculty Members of the LIMES Institute

Prof. Jürgen Bajorath, PhD	Director of Chemo- and Bioinformatics B-IT, Dahlmannstr. 2 phone: +49 (0)2 28 / 2 69 93 06 bajorath(at)bit.uni-bonn.de
Prof. Sven Burgdorf, PhD	Cellular Immunology LIMES-Institut, Carl-Troll-Str. 31 phone: +49 (0)2 28 / 73 - 6 28 25 burgdorf(at)uni-bonn.de
Prof. Michael Famulok, PhD	Director of Chemical Biology c/o Kekulé-Institut, Gerhard-Domagk-Str. 1 phone: +49 (0)2 28 / 73 - 17 87 m.famulok(at)uni-bonn.de
Prof. Michael Hoch, PhD	Director of Molecular Developmental Biology LIMES-Institut, Carl-Troll-Str. 31 phone: +49 (0)2 28 / 73 - 6 27 36 m.hoch(at)uni-bonn.de
Prof. Waldemar Kolanus, PhD	Director of Molecular Immunology LIMES-Institut, Carl-Troll-Str. 31 phone: +49 (0)2 28 / 73 - 6 27 90 wkolanus(at)uni-bonn.de
Prof. Thorsten Lang, PhD	Membrane Biochemistry LIMES-Institut, Carl-Troll-Str. 31 phone: +49 (0)2 28 / 73 - 6 28 23 thorsten.lang(at)uni-bonn.de
Prof. Günter Mayer, PhD	Chemical Biology and Chemical Genetics c/o Kekulé-Institut, Gerhard-Domagk-Str. 1 phone: +49 (0)2 28 / 73 - 48 08 gmayer(at)uni-bonn.de
Prof. Michael Pankratz, PhD	Director of Molecular Brain Physiology and Behaviour LIMES-Institut, Carl-Troll-Str. 31 phone: +49 (0)2 28 / 73 - 6 27 40 pankratz(at)uni-bonn.de
Prof. Konrad Sandhoff, PhD (em.)	Lipid Biochemistry c/o Kekulé-Institut, Gerhard-Domagk-Str 1 phone: +49 (0)2 28 / 73 - 53 46 sandhoff(at)uni-bonn.de
Prof. Joachim Schultze, MD	Director of Genomics and Immunoregulation LIMES-Institut, Carl-Troll-Str. 31 phone: +49 (0)2 28 / 73 - 6 27 86 j.schultze(at)uni-bonn.de
Prof. Christoph Thiele, PhD	Director of Biochemistry & Cell Biology of Lipids LIMES-Institut, Carl-Troll-Str. 31 phone: +49 (0)2 28 / 73 - 6 28 17 cthiele(at)uni-bonn.de
Prof. Klaus Willecke, PhD (em.)	Molecular Genetics & Cell Biology of Gap junction channels LIMES-Institut, Carl-Troll-Str. 31 phone: +49 (0)2 28 / 73 - 6 27 43 willecke(at)uni-bonn.de

Research Groups funded by the Ministry of Innovation, Science and Research of North Rhine-Westphalia

Dr. Susanne Buch, PhD	Group leader Nutrition, Gender and Metabolism LIMES-Institut, Carl-Troll-Str. 31 phone: +49 (0)2 28 / 73 - 6 27 49 sbuch(at)uni-bonn.de
Dr. Christian Kandt, PhD	Group leader Computational Structural Biology B-IT, Dahlmannstr. 2 phone: +49 (0)2 28 / 2 69 93 24 kandt(at)bit.uni-bonn.de
Priv. Doz. Dr. med. Andrea Staratschek-Jox, MD	Group leader Functional Genomics LIMES-Institut, Carl-Troll-Str. 31 phone: +49 (0)2 28 / 73 - 6 27 79 starat(at)uni-bonn.de

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